Mikey’s back and about to face his greatest challenge… his new sister.
Overview
Mollie and James are together and raising a family, which now consists of an older Mikey and his baby sister, Julie. Tension between the siblings arises, and as well with Mollie and James when Mollie's brother Stuart moves in. Mikey is also learning how to use the toilet for the first time.
Cast
John Travolta
James
Kirstie Alley
Mollie
Olympia Dukakis
Rosie
Elias Koteas
Stuart
Twink Caplan
Rona
Bruce Willis
Mikey (voice)
Roseanne Barr
Julie (voice)
Damon Wayans
Eddie (voice)
Mel Brooks
Mr. Toilet Man (voice)
Lorne Sussman
Mikey
Megan Milner
Julie (1 year)
Georgia Keithley
Julie (4 months)
Nikki Graham
Julie (newborn)
Danny Pringle
Eddie
Neal Israel
Mr. Ross
Lesley Ewen
Debbie
Noelle Parker
Woman Client
Douglas Warhit
Man Client
Terry David Mulligan
IRS Inspector
Paul Shaffer
Taxi Businessman
Don S. Davis
Dr. Fleischer
Morris Panych
Arrogant Businessman
Alex Bruhanski
Needle Doctor
Dorothy Fehr
Blonde
Heather Lea Gerdes
Hot Babe on Fire Escape
Robin Trapp
Cool Chick
Rick Avery
Burglar
Stephen Dimopoulos
Fire Chief
Jimmy Galeota
Punk Baby
Frank Totino
Candy Man
Coleman Lumley
Blonde Baby
Constance Barnes McCansh
Sexy Dancer
Ruby J. Munro
Businessman's Babe
Mollie Heckerling
Mikey's Dream Friend
Alicia Mizel
Slob Child
Aaron Jefford
Businessman (uncredited)
Denis Corbett
Cop (uncredited)
Yolanda Corbett
Shopper (uncredited)
Look Who's Talking
Look Who's Talking Now!
Don't Look Now
The Bonfire of the Vanities
She's Having a Baby
Carry On Up the Khyber
La vida no vale nada
Looney Tunes Platinum Collection: Volume One
The Thundered Man
The Beast from 20,000 Fathoms
Napoleon
To Be or Not to Be
The Big Green
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Hudson Hawk
The Forbidden Dance
Jumpin' Jack Flash
Manual of Love
Milk Money
Sugar & Spice