Cast

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  John Goodman

  The Dean (segment "Happy Birthday")

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  Sydney Tamiia Poitier

  Hannah (segment "Happy Birthday")

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  Beverly D'Angelo

  Bag Lady (segment "Happy Birthday")

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  Christopher Lloyd

  Attorney Bum (segment "Happy Birthday")

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  David Hyde Pierce

  Barney (segment "Happy Birthday")

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  Caroline Rhea

  Monica (segment "Happy Birthday")

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  Jenica Bergere

  Sally (segment "Happy Birthday")

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  Ken Hudson Campbell

  Security Guard (segment "Happy Birthday")

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  Roman Danylo

  Donald (segment "Happy Birthday")

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  Kimiko Gelman

  May Lee Ha (segment "Happy Birthday")

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  Jean Kasem

  Nurse (segment "Happy Birthday")

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  Taylor Negron

  Policeman (segment "Happy Birthday")

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  Travis Wester

  Chute Boy (segment "Happy Birthday")

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  Dondré Whitfield

  Man in Elevator (segment "Happy Birthday")

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  Marissa Jaret Winokur

  Dean's Secretary (segment "Happy Birthday")

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  Bruce Davison

  (segment "The Other Side")

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  Anthony LaPaglia

  Dr. Maas (segment "The Other Side")

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  Karen Sillas

  Anna (segment "The Other Side")

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  Andie MacDowell

  Lisa (segment "Reaching Normal")

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  Paul Rudd

  Kenneth (segment "Reaching Normal")

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  Joey Lauren Adams

  Sarah (segment "Reaching Normal")

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  Alan Rosenberg

  Frank (segment "Reaching Normal")

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  Joel Grey

  Dr. Mensley (segment "Reaching Normal")

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  Jolene Blalock

  Charlie's Wife (wraparound segments)

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  Scott Lowell

  Charlie (wraparound segments)

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  Stephen Tobolowsky

  Tom (wraparound segments)

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  Kathleen Wilhoite

  Lucy (wraparound segments)

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  Ellen DeGeneres

  Operator (segment "Reaching Normal") (uncredited)

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  Helen Mirren

  Distinguished Woman (segment "Happy Birthday") (uncredited)